The research on formulations is aimed to explore the optimum dosage forms to achieve efficient distribution of active ingredients in the body to maximize efficacy and minimize side effects.
The formulation technology is the core technology which affects success or failure of new drug development efforts and can be called a bridge of dream between drug discovery and clinical application.
Furthermore, we are engaged in the development of technology to improve patients’ compliance by enhancement of efficacy and change of dosage forms or routes of administration of existing drugs to allow easier intake.
The research on formulations is based on theories, but empirical factors for solving problems through trial and error are also important. Therefore, the Formulation Research Laboratory and Analytical Laboratory are sharing information intimately and making integrated efforts to realize clinical applications.
So far, we have accomplished various achievements such as conversion of injectables to suppositories and oral agents based on our proprietary formulation technology and technology to create prodrugs by chemical modifications.
“Orally disintegrating tablets of Kyoto (ODK)” created by our representative formulation technology are already in commercial application. We are striving to develop other successor dosage forms.